Once In A Lifetime

Once In A Lifetime Trip Itineraries is your travel resource guide to all the epic travels that you can do all over the world. I am selectively presenting this list of specific routes intersecting and covering several destinations and attractions. In the following trip itineraries (travel guides), I will be suggesting on where to stay, stop, see, and eat, and how to prepare for the trip.

Below is a list of some of the most popular travel itineraries that you can do solo or in groups. These are the kind of adventures that your heart has been craving since your childhood. Let’s do them, one at a time.

Intercontinental Travel Itineraries

Darien Gap

Gringo Trail

Istanbul to New Delhi Overland

Moscow to Urumqi

On the trail of Marco Polo

The Silk Road

The Trans-Siberian Railway

Around the World in 80 Days

World Famous Ruins

Africa Travel Itineraries

Cairo to Nairobi overland

Alexandria to Cape Town by train and bus

MV Liemba, a historic ferry

Felucca cruise on the Nile in Egypt

Garden Route in South Africa

Route 62 in South Africa

Asia Travel Itineraries

Karakoram Highway

Bangkok to Ho Chi Minh City overland

Ho Chi Minh City to Shanghai overland

Burma Road

Erlian Grassland

Tour Loop in Mongolia

Mount Kailash overland to Tibet

Caucasus Travel Itineraries

Armenia Heritage Trail

Georgian Military Highway

Janapar Trail

China Travel Itineraries

Along the Grand Canal

Along the Salween River

Along the Yangtze River

Along the Yellow River

Hong Kong to Kunming overland

Long March Tiger Leaping Gorge Yunnan tourist trail

Japan Travel Itineraries

88 Temple Pilgrimage Chugoku

33 Kannon Temple Pilgrimage

Mt. Chokai Narrow Road to the Deep North

Shimanami Kaido Bikeway

World Heritage Tour in Nara

Middle East Travel Itineraries

Golan Trail

Israel National Trail

The Jesus Trail

From Istanbul to Cairo Hajj, the Muslim pilgrimage

Mount Damavand Trek

Sea to Sea (Yam el Yam)

South Asia Travel Itineraries

Annapurna Circuit

Annapurna Sanctuary

Everest Base Camp Trek in Nepal

Grand Trunk Road

The Great Himalaya Trail

Indigenous Peoples Trail

Island PeakTrek

Manaslu Trek

Markha Valley Trek

On the trail of Kipling’s Kim

The Golden Triangle in India

World Heritage Sites Tour in Sri Lanka

South East Asia Travel Itineraries

Bangkok to Ho Chi Minh City overland

Ban Nalan Trail

Banana Pancake Trail

Jungle Railway

Kota Kinabalu to Brunei by land

Pontianak to Kuching Southern Ridges Walk

Thailand Travel Itineraries

Rattanakosin Tour

Chiang Mai to Chiang Rai

Mae Hong Son Loop

Samoeng Loop

Yaowarat and Phahurat Tour

Europe Travel Itineraries

Amber Road

Cruising the Baltic Sea

The Danube Cycleway

E9 European Coast Path

E11 hiking trail

E45 through Europe Orient Express, Paris to Istanbul

Struve Geodetic Arc

Tour du Mont Blanc

Via Baltica

Way of St. James

Ad’s Path in Belgium

Priecne Sedlo in Slovakia

Tatranska Magistrala in Slovakia

Along the Troad Coast in Turkey

Lycian Way, hiking trail in Mediterranean

Turkey Greina Walking Tour

Hiking from Zakopane to Giewont

Royal Way of Prague

The Royal-Imperial Route in Poznań

Route 1-Ring Road, around Iceland

Padjelantaleden Brașov cultural tour of Romania

Transylvania triangle train tour in Romania

Highway of the Sun in Italy

Alsatian Vineyard Route in France

The French Way in France

Santiago de Compostela from France

Britain & Ireland Travel Itineraries

Ben Nevis Ledge Route and the Carn Mor Dearg Arete (Ben Nevis)

Coast To Coast Walk

Cuckoo Trail

Driving tour of Scotland

Dylan Thomas Trail

Great Glen Way

Hikes in the Lake District

Ring of Kerry

Literary London

London South Bank Walk

The Forest Way

Offa’s Dyke Path

Oxfordshire Way

Pennine Way

Speyside Way

Southern Upland Way

South Downs Way

Prehistoric Wessex Trail

Wales Coast Path

Walk the London Wall

Western Isles Overland Route

West Highland Railway

West Highland Way

Germany Travel Itineraries

Bertha Benz Memorial Route

Romantic Road




Elbe Radweg

Nordic Countries Travel Itineraries

A seaside stroll in Helsinki in Finland

Nidaros Path

Road 63 (Norway), Geiranger-Trollstigen scenic drive

E4 through Sweden

E6 through Sweden and Norway

E10 through Sweden and Norway

European route E39, mostly Norway’s jagged west coast

Finland in 10 days by car

Göta Kanal Hurtigruten, steamer along the Norwegian coast

King’s Road in Finland

Russia Travel Itineraries

Baikal-Amur Mainline

Golden Ring

Kolyma Highway

Russia to Japan via Sakhalin

Trans-Siberian Railway

North America Travel Itineraries

North America Alaska Highway

Chilkoot Trail

Underground Railroad from the USA to Canada

Hummingbird Highway in Belize

Canada Travel Itineraries

Across Canada by train

Bruce Trail

Dempster Highway

Esker Trail

Icefields Parkway

Rideau Canal

Sunshine Coast-Vancouver Island

Circle Tour

Trans-Canada Highway and Yellowhead Highway

Trans-Labrador Highway

Windsor-Quebec corridor

Cenotes of the Yucatán in Mexico

Ruta Puuc in Mexico

Ruta del Tránsito in Nicaragua

United States Travel Itineraries

A Taste of Coastal Texas

Kaloko-Honokohau Trail

Ala Kahakai National Historic Trail

Along the Magnificent Mile

American Discovery Trail

Appalachian Trail

Braddock Expedition

California Zephyr

Canoeing the San Marcos River

Continental Divide Trail

Dalton Highway


El Camino

Real Empire Builder

Erie Canal

Floating the Missouri River and Mississippi River

From Plymouth to Hampton Roads

Iditarod Trail

The Jazz Track

Lewis and Clark Trail

Lincoln Highway Loop

Art Tour

Mountains to Sound Greenway

Natchez Trace

Oregon Trail

Pacific Coast Highway

Pacific Crest Trail (PCT)

Route 66 and Radiator Springs

Santa Fe Trail

The Mohawk Trail

The North Cascade Loop

Touring Shaker country

U.S. Highway 1

The Wire Tour

Oceania Travel Itineraries

Australia Travel Itineraries

Across Australia by train

Cape to Cape Track

Coolgardie-Esperance Highway

Eyre Highway – Great Eastern Highway

Gibb River Road

Great Northern Highway

Great Ocean Road

Gunbarrel Highway

New England Highway

North West Coastal Highway

One week in Sydney

Oodnadatta Track

Oxley Highway

Pacific Highway

Stuart Highway

Sydney to Melbourne by car

Tanami Track

Waterfall Way

New Zealand Travel Itineraries

Careys Creek Track

Milford Track

The Other 1

Rakiura Track

Rees-Dart Track

Routeburn Track

Kokoda Track in Papua New Guinea

South America Travel Itineraries

Amazon River Voyage

Colombia to Patagonia overland

Pan-American Highway

El Choro Trek in Bolivia

Jesuit Missions of the Chiquitos in Bolivia

Caminhos do Imigrante in Brazil

Estrada Real in Brazil

Along the Paraguay River in Paraguay

Inca Highlands in Peru

Inca Trail in Peru

Fantasy Itineraries

Fantasy worlds

Afterlife destinations of different religions

Lost cities

Lost lands

Phantom Islands

Mythological places